[发明专利]一组用于近视诊断及右眼柱镜筛查的SNP组合标志物及其应用

权利要求书

1.一种诊断近视的SNP位点，所述SNP位点包括以下任一组的位点组合：

1)rs42688、rs143580489、rs10484690、rs189212243；

2)rs12408385、rs2275365、rs374309842、rs77901289、rs147707514、rs143100530、、rs41298993、rs26173、rs26098、rs1353251、rs5867289、rs1494555、rs42688、rs32210、rs143580489、rs1204114、rs10484690、rs118151455、rs201920957、rs189212243、rs117569740、rs2271001、rs185257411、rs698028、rs4923849、rs12904657、rs62037369、rs13337155、rs17223038、rs199667693、rs148965154；

3)rs12408385、rs2275365、rs2275360、rs368345074、rs80002732、rs374309842、rs77901289、rs191506876、rs147707514、rs3087649、rs10177030、rs143100530、rs1434087、rs3748962、rs28900693、rs1077827、rs80341144、rs3213930、rs41298993、rs3749584、rs10517195、rs2271924、rs13147012、rs79482316、rs3827497、rs26173、rs26098、rs26107、rs26086、rs1353251、rs5867289、rs1494555、rs42688、rs32210、rs154483、rs7764126、rs13205210、rs143580489、rs1204114、rs10484690、rs118151455、rs200111157、rs113281844、rs201920957、rs79960636、rs112596877、rs117509972、rs189212243、rs74699763、rs2584、rs7023474、rs117569740、rs147367410、rs61748723、rs17849182、rs79735301、rs145978705、rs304494、rs115526095、rs7907476、rs4880361、rs2271001、rs111885243、rs2074233、rs622082、rs546382、rs185257411、rs145509540、rs144650014、rs17103265、rs11570779、rs17793018、rs76846944、rs698028、rs4923849、rs12904657、rs72765429、rs111980103、rs61737565、rs4788099、rs7198606、rs62037369、rs62037371、rs10499、rs13337155、rs61742982、rs9303742、rs17223038、rs199667693、rs148965154、rs706764、rs56408444、rs117753855、rs78472358、rs6037509、rs150212573、rs147911723、rs470101；

4)rs3795262、rs12409277、rs61735125、rs61746709、rs191051279、rs151112364、rs2291804、rs12408385、rs2275365、rs2275360、rs146696696、rs11542470、rs12386、rs74622002、rs368345074、rs142732858、rs80002732、rs374309842、rs144649977、rs78780269、rs2275863、rs77901289、rs191506876、rs117369152、rs147707514、rs6715296、rs3087649、rs7584256、rs10177030、rs11694145、rs4149520、rs143100530、rs1434087、rs77497147、rs2004888、rs11568351、rs141302000、rs3748962、rs11574750、rs16858808、rs16858811、rs141559295、rs3769838、rs6734083、rs28900693、rs4663795、rs34401965、rs76999397、rs11919775、rs1869852、rs1869851、rs1077827、rs80341144、rs3213930、rs2029618、rs75318799、rs11719458、rs33988592、rs79845192、rs41298993、rs2124541、rs66748594、rs28372853、rs572169、rs2246901、rs73189480、rs3733217、rs34611001、rs61746000、rs117486807、rs147434354、rs35762546、rs3749584、rs2271036、rs2271037、rs10517195、rs41498446、rs3733324、rs2271924、rs1801612、rs2280099、rs8582、rs13147012、rs79482316、rs3827497、rs26173、rs26098、rs26107、rs26086、rs1051489、rs2270915、rs3813474、rs1353252、rs1353251、rs1494561、rs1353250、rs5867289、rs1494558、rs1494555、rs987106、rs2233216、rs2233213、rs3217552、rs16874505、rs3749684、rs3729668、rs28388868、rs144533176、rs42688、rs32210、rs13180243、rs154483、rs367805、rs2631368、rs117231680、rs10053292、rs7701410、rs11249552、rs142883877、rs150856424、rs3734391、rs9370867、rs77229316、rs17194565、rs117487649、rs1264319、rs35756329、rs17201248、rs190135313、rs7764126、rs11755393、rs13205210、rs3734264、rs1051115、rs74609186、rs6928630、rs143580489、rs1204114、rs10484690、rs118151455、rs143904280、rs9459355、rs9459356、rs113806172、rs10227750、rs200111157、rs539973087、rs182692351、rs13306387、rs79809732、rs113281844、rs201920957、rs236652、rs236655、rs236666、rs79960636、rs112596877、rs117509972、rs772373052、rs801841、rs1062394、rs200333762、rs4301376、rs775410128、rs3987896、rs146160185、rs17171113、rs2788473、rs189212243、rs74699763、rs2584、rs41488144、rs13306550、rs77061383、rs145349678、rs371193886、rs8178175、rs4925828、rs7023474、rs3802392、rs4879781、rs35066989、rs112858544、rs1164863576、rs16909677、rs117738198、rs117569740、rs147367410、rs61748723、rs16916100、rs2297530、rs77309503、rs77564189、rs371047734、rs17849182、rs79735301、rs145978705、rs118012211、rs76191089、rs142547455、rs2073878、rs78774780、rs140120230、rs150198392、rs10600924、rs7921838、rs3829125、rs183963660、rs17134592、rs569927230、rs41382649、rs11255267、rs144121793、rs12773592、rs139646798、rs7095891、rs11003124、rs202046718、rs7076156、rs79298145、rs3758464、rs16935560、rs304494、rs304439、rs116994405、rs11553577、rs61731067、rs7100644、rs115526095、rs7907476、rs2901895、rs7912552、rs11017735、rs4880361、rs3764896、rs1056819、rs729662、rs148238084、rs138312423、rs2271001、rs111885243、rs6485702、rs326222、rs2013867、rs901746、rs2167079、rs7120118、rs1050922、rs2074233、rs77749149、rs78038516、rs11231726、rs12146487、rs182061168、rs514076、rs145270731、、rs3741172、rs1551886、rs17856219、rs1551888、rs622082、rs546382、rs488792、rs568862、rs187530720、rs2276278、rs2846412、rs143351376、rs117176605、rs10844777、rs1948516、rs2232566、rs7132546、rs12313730、rs186809868、rs35988455、rs2178685、rs73218270、rs11547907、rs9658501、rs3914、rs555404、rs10773127、rs185257411、rs145509540、rs9315569、rs953958、rs953957、rs2183207、rs4578496、rs4614565、rs151310875、rs377238277、rs144650014、rs2274827、rs17103265_rs397844079、rs11570779、rs12883882、rs17793018、rs76846944、rs2297298、rs698028、rs944050、rs2069590、rs780162072、rs73370219、rs4923849、rs12904657、rs3068、rs1046657、rs12324091、rs3743267、rs12438118、rs556233670、rs149146765、rs193114293、rs2227933、rs3214113、rs72765429、rs34855511、rs400037、rs387467、rs111980103、rs367960426、rs182015467、rs117824484、rs373109045、rs41303763、rs149271、rs180743、rs180744、rs151174、rs181206、rs61737565、rs4788099、rs7198606、rs62037369、rs62037371、rs9931989、rs10499、rs140411458、rs71220135、rs13337155、rs141238615、rs1055708、rs114991387、rs145160385、rs4796407、rs77805790、rs756223、rs61742982、rs117908897、rs9890678、rs11080105、rs3744374、rs56135703、rs117696751、rs2164449、rs150548254、rs7216513、rs148008327、rs9303742、rs148172329、rs148241618、rs12954944、rs8092674、rs146099416、rs8095031、rs2298787、rs17069506、rs17223038、rs968688、rs199667693、rs148965154、rs8102258、rs8112094、rs79579962、rs706764、rs56408444、rs4142943、rs373547599、rs28399491、rs147818341、rs16982743、rs60467951、rs117753855、rs78472358、rs9636153、rs6041749、rs6037509、rs6084431、rs7262903、rs2424943、rs2424944、rs73264111、rs41305787、rs45585744、rs17310782、rs2425007、rs3053708、rs10536288、rs61501849、rs2425014、rs117729108、rs11481073、rs1998233、rs1000411、rs33969356、rs2233884、rs2072974、rs2273086、rs3746619、rs3827103、rs35295928、rs150212573、rs147911723、rs9636833、rs138340460、rs5992854、rs201400555、rs4820658、rs11090413、rs470101。